E koho iā mākou
Loaʻa iā JDK nā hale hana papa mua a me nā lako hoʻokele maikaʻi, e hōʻoiaʻiʻo ana i ka lako paʻa o nā kikowaena API.Hōʻoia ka hui ʻoihana i ka R&D o ka huahana.E kūʻē i nā mea ʻelua, ke ʻimi nei mākou iā CMO & CDMO ma ka mākeke kūloko a me ka honua.
Hōʻike huahana
ʻO N-Acetyl-3-(3,5-difluorophenyl)-DL-alanine, a i ʻole N-acetyl-3-DFA-DL-alanine wale nō, he mea hoʻoheheʻe amino acid synthetic.Hoʻohui i nā apo acetyl, alanine a me difluorobenzene.Hāʻawi kēia ʻano molekula kūʻokoʻa iā ia i nā waiwai kūʻokoʻa, e lilo ia i mea hana waiwai ma ka noiʻi lāʻau lapaʻau a me kemika.
ʻO kekahi o nā hiʻohiʻona ʻokoʻa o N-acetyl-3-DFA-DL-alanine ʻo ia ka hiki ke kāohi i nā enzyme kikoʻī i loko o ke kino kanaka.Hiki i kēia pāpā ke loaʻa nā hopena nui i ka lāʻau lapaʻau, ʻoi aku ka maikaʻi o ka hoʻomohala ʻana i nā lāʻau lapaʻau hou no nā maʻi i hoʻopilikia ʻia e nā enzyme i kuhikuhi ʻia.Eia kekahi, ʻo kona hiki ke hoʻololi i kekahi mau kaʻina olaola ma o ka launa pū ʻana me nā mea loaʻa kikoʻī e lilo ia i waiwai waiwai i ke aʻo ʻana i nā ala physiological like ʻole.
ʻO kekahi hiʻohiʻona koʻikoʻi o kēia pūhui, ʻo ia kona hiki ke lilo i poloka kūkulu no ka synthesis o nā molekala paʻakikī ʻē aʻe.ʻO kāna versatility hiki ke hana i nā mea kemika hou, e hoʻohana nui ai i ka lāʻau lapaʻau a me ka ʻike lāʻau.Hiki i nā mea noiʻi ke hoʻohana i nā waiwai kūʻokoʻa o N-acetyl-3-DFA-DL-alanine e hoʻokumu i nā moho lāʻau lapaʻau hou me nā profile pharmacological optimized.
Eia hou, loaʻa i ka N-acetyl-3-DFA-DL-alanine ka solubility maikaʻi loa i nā mea hoʻoheheʻe polar a me nā polar ʻole, e maʻalahi i kona hoʻohana ʻana i nā kaʻina hana hoʻokolohua like ʻole.ʻO kona kūpaʻa ma lalo o nā kūlana like ʻole e hōʻoia i nā hopena hilinaʻi, e ʻae i nā mea noiʻi e hana i nā hoʻokolohua piha a loaʻa ka ʻikepili pololei.
ʻO ka maʻemaʻe a me ka maikaʻi o N-Acetyl-3-DFA-DL-Alanine he mea koʻikoʻi loa ia, a ma ke ʻano he mea hoʻolako haʻaheo, hōʻoia mākou e hoʻokō kā mākou huahana i nā kūlana kiʻekiʻe.Hoʻopili ʻia kā mākou N-Acetyl-3-DFA-DL-Alanine me ka hoʻohana ʻana i ka ʻenehana hou a me nā ana hoʻomalu maikaʻi koʻikoʻi e hōʻoia i ka kūlike a me ka hilinaʻi i kēlā me kēia pūʻulu.
